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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Teddy O'Herlihy | 2021-2033 | 29 | 12 | .707 | 4.08 | 80 | 52 | 0 | 0 | 1 | 350.2 | 376 | 159 | 30 | 81 | 277 |
| Rob O'Quinn | 2019-2023 | 10 | 13 | .435 | 3.39 | 109 | 0 | 0 | 0 | 20 | 124.2 | 128 | 47 | 12 | 31 | 115 |
| Osamu Ochi | 2024-2029 | 4 | 5 | .444 | 4.00 | 167 | 0 | 0 | 0 | 22 | 218.1 | 221 | 97 | 16 | 101 | 194 |
| Carl Odegaard | 2014-2018 | 17 | 8 | .680 | 3.60 | 133 | 0 | 0 | 0 | 9 | 165.0 | 153 | 66 | 16 | 54 | 116 |
| Jon Ohagan | 2013-2016 | 6 | 8 | .429 | 3.72 | 118 | 0 | 0 | 0 | 9 | 145.1 | 146 | 60 | 15 | 32 | 115 |
| Eisuke Oike | 2033-2034 | 1 | 2 | .333 | 5.40 | 21 | 2 | 0 | 0 | 1 | 43.1 | 40 | 26 | 8 | 23 | 37 |
| Sal Ojeda | 2014-2014 | 0 | 1 | .000 | 8.68 | 6 | 0 | 0 | 0 | 0 | 9.1 | 9 | 9 | 0 | 11 | 6 |
| Charles Olaughlin | 2013-2018 | 42 | 39 | .519 | 3.62 | 117 | 105 | 3 | 2 | 0 | 654.0 | 605 | 263 | 24 | 284 | 479 |
| Bill Olesen | 2015-2019 | 16 | 32 | .333 | 5.69 | 60 | 60 | 7 | 2 | 0 | 368.2 | 423 | 233 | 23 | 276 | 218 |
| Bartolo Olivarez | 2018-2030 | 42 | 19 | .689 | 3.26 | 81 | 79 | 16 | 8 | 1 | 558.1 | 443 | 202 | 27 | 285 | 595 |
| Javier Olivas | 2019-2020 | 1 | 2 | .333 | 8.76 | 5 | 5 | 0 | 0 | 0 | 24.2 | 40 | 24 | 4 | 15 | 4 |
| Tuan Olmstead | 2013-2019 | 42 | 27 | .609 | 3.50 | 100 | 77 | 17 | 3 | 1 | 567.2 | 540 | 221 | 44 | 164 | 432 |
| Marty Olson | 2032-2035 | 10 | 7 | .588 | 3.49 | 47 | 7 | 2 | 1 | 1 | 134.0 | 134 | 52 | 9 | 37 | 82 |
| Ambroz Ondra | 2021-2027 | 18 | 13 | .581 | 3.35 | 243 | 0 | 0 | 0 | 7 | 284.2 | 264 | 106 | 16 | 106 | 196 |
| Subaru Ono | 2030-2032 | 9 | 9 | .500 | 5.38 | 47 | 25 | 1 | 0 | 4 | 190.2 | 215 | 114 | 30 | 83 | 134 |
| Raúl Orosco | 2025-2032 | 40 | 31 | .563 | 3.49 | 137 | 93 | 1 | 1 | 1 | 632.2 | 590 | 245 | 52 | 228 | 520 |
| Diego Ortega | 2021-2027 | 6 | 17 | .261 | 6.15 | 169 | 26 | 0 | 0 | 8 | 286.2 | 372 | 196 | 18 | 154 | 178 |
| Sancho Ortega | 2032-2035 | 2 | 6 | .250 | 4.51 | 59 | 0 | 0 | 0 | 3 | 109.2 | 103 | 55 | 12 | 62 | 85 |
| James Ortis | 2014-2014 | 0 | 0 | .000 | 0.00 | 5 | 0 | 0 | 0 | 0 | 4.0 | 3 | 0 | 0 | 2 | 3 |
| Ángel Ortíz | 2021-2028 | 19 | 10 | .655 | 3.72 | 261 | 0 | 0 | 0 | 32 | 300.1 | 310 | 124 | 21 | 99 | 167 |
| Juan Ortíz | 2025-2031 | 11 | 6 | .647 | 4.62 | 91 | 0 | 0 | 0 | 6 | 85.2 | 74 | 44 | 7 | 77 | 92 |
| Miguel Ortíz | 2024-2024 | 0 | 0 | .000 | 20.25 | 2 | 0 | 0 | 0 | 0 | 1.1 | 4 | 3 | 1 | 2 | 1 |
| Darrell Osborn | 2033-2034 | 2 | 1 | .667 | 3.82 | 19 | 0 | 0 | 0 | 0 | 35.1 | 28 | 15 | 2 | 20 | 40 |
| Yasunobu Ota | 2031-2035 | 18 | 17 | .514 | 5.00 | 84 | 35 | 1 | 1 | 1 | 322.1 | 366 | 179 | 42 | 153 | 259 |
| Juan Otero | 2020-2022 | 4 | 6 | .400 | 3.41 | 60 | 0 | 0 | 0 | 19 | 66.0 | 68 | 25 | 3 | 30 | 43 |
| Anibal Ottman | 2013-2016 | 13 | 6 | .684 | 4.42 | 29 | 28 | 2 | 1 | 0 | 185.1 | 192 | 91 | 19 | 57 | 106 |
| Chet Overholt | 2014-2018 | 28 | 32 | .467 | 4.83 | 79 | 78 | 14 | 2 | 0 | 488.0 | 524 | 262 | 43 | 160 | 163 |
| Arthur Owens | 2014-2015 | 1 | 2 | .333 | 4.75 | 21 | 0 | 0 | 0 | 0 | 41.2 | 48 | 22 | 5 | 11 | 20 |
| Theodore Ozuna | 2022-2025 | 29 | 32 | .475 | 4.76 | 95 | 92 | 0 | 0 | 0 | 555.2 | 593 | 294 | 55 | 268 | 574 |
