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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Teddy O'Herlihy | 0-2028 | 11 | 6 | .647 | 2.95 | 23 | 23 | 1 | 1 | 0 | 149.2 | 138 | 49 | 13 | 29 | 159 |
| Rob O'Quinn | 0-2023 | 3 | 9 | .250 | 3.35 | 93 | 0 | 0 | 0 | 63 | 91.1 | 78 | 34 | 3 | 40 | 82 |
| Osamu Ochi | 0-2027 | 6 | 2 | .750 | 3.27 | 51 | 0 | 0 | 0 | 4 | 52.1 | 30 | 19 | 2 | 19 | 42 |
| Frank Ogrady | 1-0 | 21 | 34 | .382 | 5.23 | 74 | 74 | 9 | 1 | 0 | 481.2 | 594 | 280 | 34 | 185 | 185 |
| Eisuke Oike | 0-3 | 1 | 0 | 1.000 | 3.52 | 4 | 4 | 0 | 0 | 0 | 23.0 | 22 | 9 | 0 | 16 | 17 |
| Sal Ojeda | 0-2014 | 10 | 12 | .455 | 5.23 | 47 | 24 | 0 | 0 | 0 | 168.2 | 172 | 98 | 9 | 108 | 103 |
| Jonas Oleiro | 0-0 | 2 | 8 | .200 | 5.90 | 18 | 15 | 0 | 0 | 0 | 93.0 | 138 | 61 | 8 | 43 | 72 |
| Bill Olesen | 0-2019 | 4 | 7 | .364 | 3.68 | 13 | 13 | 4 | 1 | 0 | 102.2 | 82 | 42 | 6 | 56 | 59 |
| Bartolo Olivarez | 0-2020 | 16 | 7 | .696 | 3.26 | 25 | 25 | 2 | 0 | 0 | 182.0 | 182 | 66 | 12 | 70 | 182 |
| Javier Olivas | 5-2020 | 18 | 27 | .400 | 3.58 | 109 | 55 | 9 | 2 | 2 | 487.2 | 505 | 194 | 34 | 111 | 241 |
| Tuan Olmstead | 0-2014 | 0 | 2 | .000 | 3.66 | 3 | 3 | 0 | 0 | 0 | 19.2 | 26 | 8 | 0 | 3 | 19 |
| Marty Olson | 0-3 | 7 | 3 | .700 | 3.14 | 61 | 0 | 0 | 0 | 40 | 66.0 | 58 | 23 | 7 | 28 | 47 |
| Ambroz Ondra | 0-2022 | 2 | 1 | .667 | 2.22 | 17 | 0 | 0 | 0 | 0 | 24.1 | 26 | 6 | 0 | 5 | 17 |
| Subaru Ono | 1-2031 | 14 | 18 | .438 | 4.98 | 97 | 42 | 1 | 0 | 2 | 331.0 | 378 | 183 | 37 | 137 | 234 |
| Raúl Orosco | 0-2031 | 11 | 5 | .688 | 3.77 | 21 | 21 | 1 | 0 | 0 | 140.2 | 135 | 59 | 10 | 29 | 142 |
| Diego Ortega | 1-2022 | 7 | 1 | .875 | 2.89 | 83 | 0 | 0 | 0 | 7 | 93.1 | 83 | 30 | 5 | 35 | 78 |
| Sancho Ortega | 0-4 | 0 | 0 | .000 | 6.95 | 9 | 0 | 0 | 0 | 0 | 22.0 | 26 | 17 | 3 | 12 | 11 |
| Ángel Ortíz | 0-2028 | 15 | 9 | .625 | 2.84 | 111 | 0 | 0 | 0 | 37 | 133.0 | 117 | 42 | 9 | 47 | 92 |
| Germán Ortíz | 1-3 | 16 | 3 | .842 | 3.13 | 95 | 0 | 0 | 0 | 4 | 146.2 | 119 | 51 | 11 | 55 | 160 |
| Juan Ortíz | 1-2031 | 13 | 9 | .591 | 2.76 | 129 | 0 | 0 | 0 | 7 | 130.1 | 99 | 40 | 8 | 83 | 159 |
| Miguel Ortíz | 1-2024 | 5 | 6 | .455 | 4.33 | 46 | 7 | 0 | 0 | 3 | 99.2 | 100 | 48 | 6 | 49 | 105 |
| Yasunobu Ota | 0-2031 | 12 | 14 | .462 | 5.54 | 45 | 37 | 0 | 0 | 0 | 227.1 | 255 | 140 | 21 | 76 | 190 |
| Juan Otero | 1-2022 | 5 | 5 | .500 | 3.23 | 83 | 3 | 0 | 0 | 2 | 117.0 | 110 | 42 | 8 | 43 | 74 |
| Arthur Owens | 1-2015 | 16 | 8 | .667 | 3.71 | 152 | 0 | 0 | 0 | 5 | 262.1 | 246 | 108 | 16 | 86 | 125 |
| Theodore Ozuna | 8-2025 | 34 | 44 | .436 | 4.73 | 135 | 121 | 1 | 0 | 2 | 641.1 | 662 | 337 | 46 | 336 | 608 |
