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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Dave O'Brien | 2031-2035 | .282 | 111 | 328 | 0 | 0 | 0 | 0.00 | 0 |
| Pete O'Bryan | 2023-2023 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Alan O'Ferrall | 2027-2027 | .171 | 0 | 8 | 0 | 0 | 0 | 0.00 | 0 |
| Teddy O'Herlihy | 2021-2032 | .127 | 0 | 18 | 78 | 46 | 8 | 4.25 | 852 |
| Bill O'Neil | 2023-2030 | .283 | 40 | 292 | 0 | 0 | 0 | 0.00 | 0 |
| Rob O'Quinn | 2020-2025 | .125 | 0 | 0 | 15 | 17 | 7 | 4.66 | 215 |
| Mauro Ocascio | 2024-2029 | .239 | 44 | 150 | 0 | 0 | 0 | 0.00 | 0 |
| Carl Odegaard | 2012-2015 | .000 | 0 | 0 | 9 | 4 | 1 | 4.84 | 39 |
| Gerald Odum | 2008-2014 | .263 | 28 | 314 | 0 | 0 | 0 | 0.00 | 0 |
| Jon Ohagan | 2015-2015 | .000 | 0 | 0 | 0 | 0 | 0 | 6.52 | 4 |
| José Ojeda | 2021-2021 | .056 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| John Okane | 2003-2022 | .087 | 1 | 52 | 277 | 170 | 1 | 3.51 | 3419 |
| Charles Olaughlin | 2009-2017 | .091 | 2 | 7 | 27 | 28 | 0 | 5.14 | 402 |
| Bill Olesen | 2011-2016 | .075 | 0 | 7 | 38 | 41 | 0 | 4.89 | 388 |
| Bartolo Olivarez | 2018-2029 | .104 | 1 | 17 | 75 | 87 | 2 | 5.02 | 1286 |
| Juan Olivarria | 2004-2006 | .205 | 0 | 10 | 13 | 32 | 0 | 5.20 | 232 |
| Roberto Olivas | 2002-2011 | .086 | 2 | 29 | 98 | 108 | 1 | 4.28 | 1052 |
| Salvador Olivas | 2029-2031 | .163 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Richard Oliver | 2023-2024 | .255 | 4 | 49 | 0 | 0 | 0 | 0.00 | 0 |
| Ezra Olivera | 2012-2012 | .143 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Alfredo Olivo | 2018-2020 | .211 | 1 | 5 | 0 | 0 | 0 | 0.00 | 0 |
| Tuan Olmstead | 2015-2025 | .127 | 0 | 20 | 69 | 89 | 1 | 4.85 | 1180 |
| Marty Olson | 2033-2035 | .000 | 0 | 0 | 12 | 35 | 2 | 6.15 | 170 |
| Alfredo Olvera | 2026-2031 | .193 | 13 | 46 | 0 | 0 | 0 | 0.00 | 0 |
| Ambroz Ondra | 2022-2027 | .167 | 0 | 0 | 4 | 3 | 3 | 4.45 | 70 |
| Ryan Oquinn | 2004-2014 | .279 | 26 | 155 | 0 | 0 | 0 | 0.00 | 0 |
| Francisco Orama | 2032-2034 | .234 | 17 | 56 | 0 | 0 | 0 | 0.00 | 0 |
| Esteban Ordóñez | 2016-2033 | .292 | 182 | 859 | 0 | 0 | 0 | 0.00 | 0 |
| Michael Orme | 2008-2011 | .180 | 2 | 22 | 0 | 0 | 0 | 0.00 | 0 |
| Erubiel Ornelas | 2011-2011 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Raúl Orosco | 2026-2031 | .222 | 0 | 0 | 15 | 16 | 18 | 6.57 | 186 |
| Hector Orozco | 2007-2020 | .100 | 2 | 27 | 125 | 121 | 16 | 4.24 | 1968 |
| Carlos Ortega | 2034-2035 | .234 | 8 | 30 | 0 | 0 | 0 | 0.00 | 0 |
| Carlos Ortega | 2025-2033 | .271 | 209 | 630 | 0 | 0 | 0 | 0.00 | 0 |
| Carlos Ortega | 2027-2031 | .285 | 38 | 187 | 0 | 0 | 0 | 0.00 | 0 |
| Pedro Ortega | 2002-2002 | .038 | 0 | 0 | 3 | 7 | 0 | 5.55 | 53 |
| Raul Ortega | 2015-2029 | .289 | 431 | 1408 | 0 | 0 | 0 | 0.00 | 0 |
| James Ortis | 2009-2014 | .118 | 0 | 1 | 2 | 1 | 0 | 4.74 | 77 |
| Ángel Ortíz | 2020-2022 | .071 | 0 | 0 | 3 | 2 | 5 | 5.54 | 58 |
| Arturo Ortiz | 2017-2020 | .269 | 14 | 90 | 0 | 0 | 0 | 0.00 | 0 |
| Javier Ortíz | 2029-2035 | .317 | 160 | 558 | 0 | 0 | 0 | 0.00 | 0 |
| Juan Ortíz | 2030-2030 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 2 |
| Miguel Ortíz | 2027-2027 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Frank Osborne | 2005-2019 | .106 | 1 | 34 | 167 | 217 | 1 | 4.20 | 3384 |
| Greg Osborne | 2032-2032 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Anibal Ottman | 2014-2022 | .174 | 2 | 47 | 99 | 86 | 0 | 4.28 | 1446 |
| Igor Overdevest | 2021-2023 | .268 | 4 | 38 | 0 | 0 | 0 | 0.00 | 0 |
| Chet Overholt | 2011-2014 | .214 | 0 | 0 | 1 | 6 | 0 | 4.88 | 25 |
| Kaoru Oyama | 2022-2026 | .273 | 11 | 115 | 0 | 0 | 0 | 0.00 | 0 |
| Theodore Ozuna | 2023-2023 | .000 | 0 | 0 | 1 | 1 | 0 | 7.45 | 19 |
