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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabry, Adil | C | Philadelphia Hornets | 22 | 02/06/2014 | Bushenyi | UGA | Right | Right | 6' 2" | 205 lbs | $450,000 |
| Salazar, Alberto | SP | Milwaukee Meerkats | 26 | 04/22/2010 | Alquízar | CUB | Left | Right | 6' 3" | 195 lbs | $300,000 |
| Salazar, Miguel | 1B | Brick Barracudas | 19 | 10/01/2016 | Varadero | CUB | Right | Right | 6' 4" | 210 lbs | - |
| Salazar, Pedro | 2B | Houston Armadillos | 30 | 04/07/2006 | Guilford | USA | Right | Right | 5' 10" | 195 lbs | $300,000 |
| Salazar, Roberto | SP | New Orleans Crawdaddy's | 16 | 05/17/2020 | Cambita Garabitos | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Salcido, Ernesto | LF | Wilmington Atlantics | 31 | 10/10/2004 | Aguascalientes | MEX | Switch | Right | 6' 1" | 195 lbs | $3,570,000 |
| Salgado, Félix | 2B | Antelope Valley Raptors | 31 | 04/17/2005 | West Bridgewater | USA | Right | Right | 6' 0" | 230 lbs | $5,500,000 |
| Salinas, António | SP | Free Agent | 36 | 02/18/2000 | Cali | COL | Right | Right | 6' 7" | 230 lbs | - |
| Samurakami, Noriaki | SP | Brooklyn Wolves | 17 | 01/28/2019 | Tokyo | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Sánchez, Adrián | 2B | Appalachian Black Bears | 35 | 09/12/2001 | Maracaibo | VEN | Right | Right | 6' 1" | 220 lbs | $650,000 |
| Sánchez, Héctor | RP | Houston Armadillos | 33 | 01/03/2003 | Ciego de Avila | CUB | Right | Right | 6' 2" | 235 lbs | $580,000 |
| Sánchez, Jorge | SP | Brick Barracudas | 16 | 01/24/2020 | La Chorrera | PAN | Left | Right | 6' 6" | 195 lbs | - |
| Sánchez, José | SP | Antelope Valley Raptors | 26 | 06/29/2010 | Guantanamo | CUB | Right | Right | 6' 5" | 210 lbs | $300,000 |
| Sánchez, Mauro | SS | Houston Armadillos | 30 | 02/18/2006 | Dajabón | DOM | Right | Right | 6' 2" | 210 lbs | $300,000 |
| Sánchez, Miguel | RP | Philadelphia Hornets | 28 | 04/23/2008 | Havana | CUB | Right | Right | 6' 7" | 220 lbs | $300,000 |
| Sandoval, Héctor | SP | Chicago Reapers | 17 | 06/19/2019 | Mayagüez | PUR | Left | Left | 6' 2" | 175 lbs | - |
| Santiago, Juan | SP | New Orleans Crawdaddy's | 31 | 07/18/2005 | Havana | CUB | Switch | Right | 6' 6" | 225 lbs | $19,000,000 |
| Santos, Enrique | SP | Milwaukee Meerkats | 24 | 01/09/2012 | Guantanamo | CUB | Left | Left | 6' 2" | 205 lbs | $300,000 |
| Santos, José | SP | Milwaukee Meerkats | 18 | 10/03/2017 | Pachuca | MEX | Right | Right | 6' 2" | 170 lbs | - |
| Santos, León | CF | Antelope Valley Raptors | 28 | 03/29/2008 | Maracaibo | VEN | Switch | Right | 6' 3" | 210 lbs | $300,000 |
| Sato, Hiroshi | LF | Milwaukee Meerkats | 17 | 11/09/2018 | Nagoya | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Saucedo, Mauro | RP | Antelope Valley Raptors | 32 | 11/10/2003 | Tocumen | PAN | Left | Right | 6' 4" | 250 lbs | $650,000 |
| Savoie, Tom | RP | Atlanta Hurricanes | 31 | 02/01/2005 | Kanata | CAN | Right | Right | 6' 0" | 245 lbs | $750,000 |
| Scott, Dana | SP | Free Agent | 21 | 07/13/2015 | Pomona | USA | Right | Right | 6' 6" | 200 lbs | - |
| Sepúlveda, José | RF | Philadelphia Hornets | 16 | 11/02/2019 | Bonao | DOM | Left | Left | 6' 1" | 175 lbs | - |
| Sepúlveda, Sergio | RP | Toronto Beavers | 27 | 07/30/2009 | Tirrases | CRC | Switch | Right | 6' 2" | 195 lbs | $300,000 |
| Serrano, Luis | LF | Wilmington Atlantics | 26 | 01/31/2010 | Pittsburgh | USA | Right | Right | 6' 2" | 200 lbs | $300,000 |
| Settignano, Yvon | LF | Chicago Reapers | 36 | 01/19/2000 | Salerno | ITA | Left | Left | 5' 10" | 220 lbs | $2,200,000 |
| Shields, Eugene | RF | Free Agent | 20 | 01/03/2016 | South Pasadena | USA | Left | Left | 6' 6" | 195 lbs | - |
| Shimizu, Masahiro | SP | Atlanta Hurricanes | 19 | 05/25/2017 | Moriyama | JPN | Left | Left | 6' 0" | 170 lbs | - |
| Sims, Mike | SP | Wilmington Atlantics | 16 | 12/27/2019 | Toronto | CAN | Right | Left | 6' 2" | 175 lbs | - |
| Singleton, Russ | SP | Antelope Valley Raptors | 31 | 12/26/2004 | Avondale | USA | Left | Left | 5' 11" | 195 lbs | $17,480,000 |
| Slater, Christian | SP | Chicago Reapers | 19 | 09/16/2016 | Cabo Rojo | PUR | Right | Right | 6' 5" | 190 lbs | - |
| Smith, Dominic | SS | New Orleans Crawdaddy's | 30 | 11/22/2005 | Seattle | USA | Right | Right | 6' 1" | 225 lbs | $300,000 |
| Smith, Tim | RF | New Orleans Crawdaddy's | 25 | 10/17/2010 | Milwaukee | USA | Left | Left | 6' 4" | 215 lbs | $300,000 |
| Solís, Sergio | LF | Chicago Reapers | 34 | 05/14/2002 | Camajuaní | CUB | Right | Right | 6' 0" | 210 lbs | $18,000,000 |
| Soto, Manny | SP | Milwaukee Meerkats | 18 | 04/07/2018 | Venezuela | CUB | Right | Right | 6' 4" | 180 lbs | - |
| Souza, Jesús | 2B | Toronto Beavers | 30 | 02/04/2006 | Saint Paul | USA | Right | Right | 6' 2" | 210 lbs | $1,350,000 |
| Sparks, Shawn | RP | Brick Barracudas | 27 | 11/19/2008 | Warren | USA | Switch | Right | 6' 4" | 225 lbs | $3,900,000 |
| Spooner, Daniel | RP | Milwaukee Meerkats | 26 | 12/30/2009 | Shelby | USA | Left | Left | 6' 4" | 245 lbs | $420,000 |
| Stafford, Melvin | 1B | Free Agent | 23 | 09/26/2012 | Flower Mound | USA | Right | Right | 6' 7" | 240 lbs | - |
| Stone, Jason | C | Free Agent | 21 | 12/31/2014 | Corpus Christi | USA | Right | Right | 6' 3" | 215 lbs | - |
| Suárez, Sergio | 2B | Brick Barracudas | 28 | 06/05/2008 | Caucagüita | VEN | Right | Right | 6' 2" | 220 lbs | $4,390,000 |
| Sullivan, Zach | RP | Brooklyn Wolves | 33 | 08/04/2003 | The Bronx | USA | Right | Right | 6' 3" | 215 lbs | $1,400,000 |
| Suzuki, Michihiro | CF | Milwaukee Meerkats | 18 | 02/08/2018 | Sendai | JPN | Right | Right | 6' 2" | 180 lbs | - |
| Suzuki, Tadayoshi | SS | Chicago Reapers | 16 | 11/02/2019 | Fukaya | JPN | Switch | Right | 6' 2" | 185 lbs | - |
| Suzuki, Takafumi | SP | Brooklyn Wolves | 20 | 07/11/2016 | Goshogawara | JPN | Right | Right | 6' 3" | 185 lbs | - |
